The 2026 ESMO LBA Landscape: Visualized

Which mechanisms are commanding the late-breaker spotlight this year?
Our analysts crunched the numbers across all LBAs:
✔️ADCs lead the field — nearly a third of all LBA drugs, spanning NSCLC, breast, ovarian, and beyond
✔️Checkpoint inhibition isn’t just a category — it’s still the default combo partner, showing up alongside ADCs, vaccines, PARP inhibitors and more
✔️Beyond PD-(L)1 and the usual ADC targets (HER2, TROP-2, B7-H3), RAS/KRAS momentum is continuing from ASCO
Stay ahead of the competitive curve with verified insights.
- Lung
- PARP inhibitors
- vaccines
- Checkpoint inhibition
- ADC targets
- PD-(L)1
- RAS
- B7-H3
- TROP-2
- HER2
- ADCs
- SCLC
- Oncology
- clinical data
- KRAS
- ESMO 2026
- NSCLC
- +14
